Wnt/beta- catenin Signaling Issues

 


Wnt/beta-catenin signaling and disease.

 

Wnt/beta-Catenin Signaling, Disease, and Emerging Therapeutic Modalities.

 

Wnt/beta-catenin signaling: components, mechanisms, and diseases.

 

Wnt/beta-catenin signaling in development and disease.

 

Wnt/beta-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology.

 

Wnt/beta-Catenin Signaling and Obesity.

 

Wnt/beta-catenin Signaling in Osteoarthritis and in Other Forms of Arthritis.

 

Wnt/beta-Catenin Signaling as a Molecular Target by Pathogenic Bacteria.

 

Wnt/beta-catenin signaling as a useful therapeutic target in hepatoblastoma.

 

Wnt/beta-Catenin Signaling in Liver Cancers.

 

Wnt/beta-catenin signaling: a promising new target for fibrosis diseases.

 

Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates.

 

Therapeutic potential of targeting the Wnt/beta-catenin signaling pathway in colorectal cancer.

 

WNT/beta-Catenin Signaling Pathway Regulating T Cell-Inflammation in the Tumor Microenvironment.

 

Multi-layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/beta-catenin signaling activation (Review).

 

Restoring Wnt/beta-catenin signaling is a promising therapeutic strategy for Alzheimer's disease.

 

Wnt/beta-Catenin Signaling: The Culprit in Pancreatic Carcinogenesis and Therapeutic Resistance.

 

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors.

 

Crosstalk between Wnt/beta-Catenin and NF-kappaB Signaling Pathway during Inflammation.

 

Wnt/beta-Catenin Signaling in Oral Carcinogenesis.

 

Wnt/beta-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs.

 

WNT/beta-catenin signaling in the development of liver cancers.

 

Wnt/beta-Catenin Signaling Pathway Governs a Full Program for Dopaminergic Neuron Survival, Neurorescue and Regeneration in the MPTP Mouse Model of Parkinson's Disease.

 

The role of the wnt/beta-catenin signaling pathway in formation and maintenance of bone and teeth.

 

Targeting the Wnt/beta-catenin signaling pathway in cancer.

 

Wnt/beta-catenin signaling and small molecule inhibitors.

 

Wnt/beta-catenin Signaling in Tissue Self-Organization.

 

Wnt/beta-catenin pathway: modulating anticancer immune response.

 

Wnt/beta-catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind.

 

Wnt/beta-catenin signaling links embryonic lung development and asthmatic airway remodeling.

 

Interplay Between SOX9, Wnt/beta-Catenin and Androgen Receptor Signaling in Castration-Resistant Prostate Cancer.

 

Wnt/beta-catenin signaling during early vertebrate neural development.

 

Wnt/beta-catenin signaling in adult mammalian epithelial stem cells.

 

Cell-cell adhesion: linking Wnt/beta-catenin signaling with partial EMT and stemness traits in tumorigenesis.

 

Frizzled and LRP5/6 receptors for Wnt/beta-catenin signaling.

 

Targeting Wnt/beta-catenin pathway in hepatocellular carcinoma treatment.

 

Role of Wnt/beta-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer.

 

Atypical regulators of Wnt/beta-catenin signaling as potential therapeutic targets in Hepatocellular Carcinoma.

 

Wnt/beta-catenin signalling and podocyte dysfunction in proteinuric kidney disease.

 

Microglia Polarization, Gene-Environment Interactions and Wnt/beta-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain.

 

New Advances in Canonical Wnt/beta-Catenin Signaling in Cancer.

 

[Screening for Chemical Suppressors of the Wnt/beta-catenin Signaling Pathway].

 

Wnt signaling in development and tissue homeostasis.

 

The regulation of beta-catenin activity and function in cancer: therapeutic opportunities.

 

Wnt/beta-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis.

 

The roles of Wnt/beta-catenin signaling pathway related lncRNAs in cancer.

 

MicroRNAs target the Wnt/beta-catenin signaling pathway to regulate epithelial-mesenchymal transition in cancer (Review).

 

Revisiting the role of Wnt/beta-catenin signaling in prostate cancer.

 

The beta-catenin destruction complex.

 

Discovery of chemical probes that suppress Wnt/beta-catenin signaling through high-throughput screening.

 

The crosstalk between microRNAs and the Wnt/beta-catenin signaling pathway in cancer.

 

Distinct Roles of Wnt/beta-Catenin Signaling in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis.

 

WNT/beta-Catenin Signaling in Vertebrate Eye Development.

 

Wnt Signaling in Cancer: Not a Binary ON:OFF Switch.

 

The Role Played by Wnt/beta-Catenin Signaling Pathway in Acute Lymphoblastic Leukemia.

 

Regulation of Wnt/beta-catenin signaling by herpesviruses.

 

Wnt Signaling in Kidney Development and Disease.

 

Roles of Wnt/beta-Catenin Signaling Pathway Regulatory Long Non-Coding RNAs in the Pathogenesis of Non-Small Cell Lung Cancer.

 

Wnt/beta-catenin signaling and kidney fibrosis.

 

Wnt/beta-catenin signaling and renin-angiotensin system in chronic kidney disease.

 

WNT signalling in prostate cancer.

 

Interactions between TGF-beta1, canonical WNT/beta-catenin pathway and PPAR gamma in radiation-induced fibrosis.

 

Wnt/beta-Catenin Signaling Pathway in Skin Carcinogenesis and Therapy.

 

Interplay Between Autophagy and Wnt/beta-Catenin Signaling in Cancer: Therapeutic Potential Through Drug Repositioning.

 

Interplay Between Ion Channels and the Wnt/beta-Catenin Signaling Pathway in Cancers.

 

New Insights about the Wnt/beta-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?

 

Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/beta-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis.

 

Discovery of small molecule inhibitors of the Wnt/beta-catenin signaling pathway by targeting beta-catenin/Tcf4 interactions.

 

WNT Signaling in Tumors: The Way to Evade Drugs and Immunity.

 

Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options.

 

Regulation of Wnt/beta-catenin signaling within and from osteocytes.

 

Circular RNAs Regulate Cancer Onset and Progression via Wnt/beta-Catenin Signaling Pathway.

 

Epigenetic Activation of Wnt/beta-Catenin Signaling in NAFLD-Associated Hepatocarcinogenesis.

 

Wnt/beta-catenin signaling in kidney injury and repair: a double-edged sword.

 

Mucins and Wnt/beta-catenin signaling in gastrointestinal cancers: an unholy nexus.

 

The Emerging Roles of Cancer Stem Cells and Wnt/Beta-Catenin Signaling in Hepatoblastoma.

 

Wnt signaling in intestinal inflammation.

 

The function of endocytosis in Wnt signaling.

 

A role for WNT/beta-catenin signaling in the neural mechanisms of behavior.

 

FoxM1 and Wnt/beta-catenin signaling in glioma stem cells.

 

Signaling mechanisms of the epithelial-mesenchymal transition.

 

Wnt/beta-Catenin Signaling in Vertebrate Posterior Neural Development.

 

Wnt/beta-catenin signaling in oral tissue development and disease.

 

Alterations of Wnt/beta-catenin signaling pathway in hepatocellular carcinomas associated with hepatitis C virus.

 

Interplay between Wnt/beta-catenin signaling and HIV: virologic and biologic consequences in the CNS.

 

Wnt/beta-catenin signaling in T-cell immunity and cancer immunotherapy.

 

The Wnt/beta-catenin signaling pathway as a target in drug discovery.

 

Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers.

 

Cross-talk between Wnt/beta-catenin and Hippo signaling pathways: a brief review.

 

Convergence between Wnt-beta-catenin and EGFR signaling in cancer.

 

Genomic insights into WNT/beta-catenin signaling.

 

Wnt/beta-catenin signaling plays a key role in the development of spondyloarthritis.

 

[Aerobic glycolysis activation through canonical WNT/beta-catenin pathway in ALS].

 

Wnt/beta-catenin signaling in adipogenesis and metabolism.

 

Alcohol consumption, Wnt/beta-catenin signaling, and hepatocarcinogenesis.

Regulation of the Wnt/beta-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 Oncoproteins.

 

A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers.

 

beta-catenin-dependent Wnt signaling in C. elegans: teaching an old dog a new trick.

 

Wnt/beta-catenin signaling: new (and old) players and new insights.

 

The Wnt/beta-catenin signaling pathway in liver biology and disease.

 

Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.

 

Role of Wnt/beta-catenin signaling in liver metabolism and cancer.

 

Wnt/beta-catenin and sex hormone signaling in endometrial homeostasis and cancer.

 

Modulation of Wnt/beta-catenin signaling pathway by bioactive food components.

 

Wnt/beta-catenin and its diverse physiological cell signaling pathways in neurodegenerative and neuropsychiatric disorders.

 

Modulation of Inflammatory Responses by Wnt/beta-Catenin Signaling in Dendritic Cells: A Novel Immunotherapy Target for Autoimmunity and Cancer.

 

Convergence of Wnt, beta-catenin, and cadherin pathways.

 

EGCG Mediated Targeting of Deregulated Signaling Pathways and Non-Coding RNAs in Different Cancers: Focus on JAK/STAT, Wnt/beta-Catenin, TGF/SMAD, NOTCH, SHH/GLI, and TRAIL Mediated Signaling Pathways.

 

Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease.

 

Wnt/beta-catenin pathway in arrhythmogenic cardiomyopathy.

 

Wnt/beta-catenin signaling and cardiogenesis: timing does matter.

 

The WNT/beta-catenin dependent transcription: A tissue-specific business.

 

Flavonoids and Wnt/beta-catenin signaling: potential role in colorectal cancer therapies.

 

Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition.

 

The Signaling of Cellular Senescence in Diabetic Nephropathy.

 

Development of anticancer agents targeting the Wnt/beta-catenin signaling.

 

Crosstalk between the TGF-beta and WNT signalling pathways during cardiac fibrogenesis.

 

A glimpse of the pathogenetic mechanisms of Wnt/beta-catenin signaling in diabetic nephropathy.

 

Action and function of Wnt/beta-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.

 

Estrogen regulation of Dkk1 and Wnt/beta-Catenin signaling in neurodegenerative disease.

 

Wnt some lose some: transcriptional governance of stem cells by Wnt/beta-catenin signaling.

 

The Wnt/beta-catenin signaling pathway controls the inflammatory response in infections caused by pathogenic bacteria.

 

Wnt/beta-Catenin Target Genes in Colon Cancer Metastasis: The Special Case of L1CAM.

 

Crosstalk between Wnt/beta-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy.

 

Wnt/beta-catenin pathway.

 

Regulation of Wnt/beta-catenin signaling by protein kinases.

 

Flavonoids: potential Wnt/beta-catenin signaling modulators in cancer.

 

Transcriptional Regulation of Wnt/beta-Catenin Pathway in Colorectal Cancer.

Assembly and architecture of the Wnt/beta-catenin signalosome at the membrane.

 

Cross Talk between Wnt/beta-Catenin and CIP2A/Plk1 Signaling in Prostate Cancer: Promising Therapeutic Implications.

 

Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy.

 

Regulation of Wnt/beta-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.

 

The Wnt/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality.

 

 Toggling a conformational switch in Wnt/beta-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexes.

 

Regulation of bone metabolism by Wnt signals.

 

Renal Tubule Repair: Is Wnt/beta-Catenin a Friend or Foe?

 

Targeting Wnt/beta-Catenin Pathway for Developing Therapies for Hair Loss.

 

Wnt Signaling in Gynecologic Malignancies.

 

Targeting the Canonical WNT/beta-Catenin Pathway in Cancer Treatment Using Non-Steroidal Anti-Inflammatory Drugs.

 

Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond.

 

Small molecules from natural products targeting the Wnt/beta-catenin pathway as a therapeutic strategy.

 

Role of beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate.

 

beta-Catenin: A Metazoan Filter for Biological Noise?

 

beta-catenin signaling: a novel mediator of fibrosis and potential therapeutic target.

 

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.

 

Genetic analysis: Wnt and other pathways in nonsyndromic tooth agenesis.

 

Targeting the canonical Wnt/beta-catenin pathway in hematological malignancies.

 

Current Understanding on EGFR and Wnt/beta-Catenin Signaling in Glioma and Their Possible Crosstalk.

 

Targeting the canonical Wnt/beta-catenin pathway in cancer radioresistance: Updates on the molecular mechanisms.

 

Wnt/beta-catenin, an oncogenic pathway targeted by H. pylori in gastric carcinogenesis.

 

Nature-derived compounds modulating Wnt/ beta -catenin pathway: a preventive and therapeutic opportunity in neoplastic diseases.

 

Extrinsic control of Wnt signaling in the intestine.

 

Wnt Signaling: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma.

 

Crosstalk between long non-coding RNAs and Wnt/beta-catenin signalling in cancer.

 

Epithelial Mesenchymal and Endothelial Mesenchymal Transitions in Hepatocellular Carcinoma: A Review.

 

Curcumin: a therapeutic strategy in cancers by inhibiting the canonical WNT/beta-catenin pathway.

 

beta-Catenin: oncogenic role and therapeutic target in cervical cancer.

 

Glucocorticoids Influencing Wnt/beta-Catenin Pathway; Multiple Sites, Heterogeneous Effects.

 

Aptamers and their potential to selectively target aspects of EGF, Wnt/beta-catenin and TGFbeta-smad family signaling.

 

Role of Metformin on Osteoblast Differentiation in Type 2 Diabetes.

 

The central role of inflammatory signaling in the pathogenesis of myelodysplastic syndromes.

The Role of Wnt Pathway in the Pathogenesis of OA and Its Potential Therapeutic Implications in the Field of Regenerative Medicine.

 

Introduction to cerebral cavernous malformation: a brief review.

 

The Role of Canonical Wnt Signaling in Regulating Radioresistance.

 

beta catenin in health: A review.

 

Chronic ulcerative colitis and colorectal cancer.

 

The research progress of the interactions between miRNA and Wnt/beta-catenin signaling pathway in breast cancer of human and mice .

 

Molecular mechanisms involved in podocyte EMT and concomitant diabetic kidney diseases: an update.

 

Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.

 

Wnt and the Wnt signaling pathway in bone development and disease.

 

Gut Microbiota: An Integral Moderator in Health and Disease.

 

Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs.

 

Wnt/beta-catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration.

 

Role and regulation of beta-catenin signaling during physiological liver growth.

 

Molecular and Cellular Pathogenesis of Endometriosis.

 

Synaptic Wnt/GSK3beta Signaling Hub in Autism.

 

Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies.

 

Wnt signaling in cartilage development and diseases: lessons from animal studies.

 

P53 mutations in colorectal cancer - molecular pathogenesis and pharmacological reactivation.

 

Therapeutic potential of umbilical cord mesenchymal stem cells with Wnt/beta-catenin signaling pathway pre-activated for the treatment of diabetic wounds.

 

Role of the Wnt/beta-catenin pathway in gastric cancer: An in-depth literature review.

 

Wnt Signaling in Renal Cell Carcinoma.

 

Interaction between Wnt/beta-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of beta-catenin and RAS by targeting the Wnt/beta-catenin pathway.

 

A growing field: The regulation of axonal regeneration by Wnt signaling.

 

Opposite Interplay Between the Canonical WNT/beta-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas.

 

Wnt Signaling Polarizes C. elegans Asymmetric Cell Divisions During Development.

 

MITF in melanoma: mechanisms behind its expression and activity.

 

Emerging role of the beta-catenin-PPARgamma axis in the pathogenesis of colorectal cancer.

 

PM2.5, Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition?

 

Scarless wound healing: finding the right cells and signals.

 

Intracellular signaling pathway regulation of myelination and remyelination in the CNS.

 

Regulatory Mechanisms of the Wnt/beta-Catenin Pathway in Diabetic Cutaneous Ulcers.

 

Ubiquitination in Scleroderma Fibrosis and Its Treatment.

 

Interaction of viral oncogenic proteins with the Wnt signaling pathway.

 

The R-spondin protein family.

 

Evolving insights into the cellular and molecular pathogenesis of fibrosis in systemic sclerosis.

 

Genome-wide analysis of canonical Wnt target gene regulation in Xenopus tropicalis challenges beta-catenin paradigm.

 

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities.

 

How do they do Wnt they do?: regulation of transcription by the Wnt/beta-catenin pathway.