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Choline

Neuroprotective Actions of Dietary Choline.

 

Neuroprotective Effects of Choline and Other Methyl Donors.

 

Neuroprotective properties of citicoline: facts, doubts and unresolved issues.

 

Citicoline and Retinal Ganglion Cells: Effects on Morphology and Function.

 

Neuropharmacological review of the nootropic herb Bacopa monnieri.

 

Cholinergic nervous system and glaucoma: From basic science to clinical applications.

 

Citicoline: pharmacological and clinical review, 2006 update.

 

Cytidine 5'-Diphosphocholine (Citicoline): Evidence for a Neuroprotective Role in Glaucoma.

 

Citicoline - a neuroprotector with proven effects on glaucomatous disease.

 

Citicoline for Acute Ischemic Stroke: A Systematic Review and Formal Meta-analysis of Randomized, Double-Blind, and Placebo-Controlled Trials.

 

Phospholipid and Lipid Derivatives as Potential Neuroprotective Compounds.

 

Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications.

 

The role of citicoline in cognitive impairment: pharmacological characteristics, possible advantages, and doubts for an old drug with new perspectives.

 

The neuroprotective role of citicoline treatment in glaucoma - 6 months results of a prospective therapeutic trial.

 

"Brain-specific" nutrients: a memory cure?

 

Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study.

 

Neuroprotective actions of perinatal choline nutrition.

 

Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipid with a still interesting profile as cognition enhancing agent.

 

Choline and the Brain: An Epigenetic Perspective.

 

CDP-choline: pharmacological and clinical review.

 

PACAP and its role in primary headaches.

 

Neuroprotective therapy.

 

Citicoline preclinical and clinical update 2009-2010.

 

Cholinesterase as a Target for Drug Development in Alzheimer's Disease.

 

Amyloid toxicity and platelet-activating factor signaling.

 

Neuroprotective Effect of Citicoline Eye Drops on Corneal Sensitivity After LASIK.

 

Frontotemporal dementia and pharmacologic interventions.

 

Membrane stabilizer: citicoline.

 

Cytidine 5'-Diphosphocholine (Citicoline) in Glaucoma: Rationale of Its Use, Current Evidence and Future Perspectives.

 

Citicoline: neuroprotective mechanisms in cerebral ischemia.

 

Target brain: neuroprotection and neurorestoration in ischemic stroke.

 

The effects of dietary choline.

 

Alzheimer's disease and epigenetic diet.

 

Neuroprotection and recovery: recent data at the bench on citicoline.

 

Investigational therapies for ischemic stroke: neuroprotection and neurorecovery.

 

CDP-choline is not protective in the SOD1-G93A mouse model of ALS.

 

Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats.

 

Neuroprotective effects of Ginkgo biloba extract.

 

Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect.

 

Neuropeptides in nasal mucosa.

 

Melanocortins and the cholinergic anti-inflammatory pathway.

 

Agonists that stimulate secretion promote the recruitment of CFTR into membrane lipid microdomains.

 

Preventing childhood and lifelong disability: Maternal dietary supplementation for perinatal brain injury.

 

Peri-arterial Autonomic Innervation of the Human Ear.

 

Neurosurgical trauma in Japan.

 

Prenatal treatment of Down syndrome: a reality?

 

Neurochemical alterations in methamphetamine-dependent patients treated with cytidine-5'-diphosphate choline: a longitudinal proton magnetic resonance spectroscopy study.

 

A meta-analysis of the effect of different neuroprotective drugs in management of patients with traumatic brain injury.

 

Citicoline in addictive disorders: a review of the literature.

 

Targeting the brain: neuroprotection and neurorestoration in ischemic stroke.

 

Nutrients for prevention and treatment of mental health disorders.

 

The effects of citicoline on acute ischemic stroke: a review.

 

Magnetic resonance spectroscopy biomarkers in term perinatal asphyxial encephalopathy: from neuropathological correlates to future clinical applications.

 

Pharmacodynamics of citicoline relevant to the treatment of glaucoma.

 

Retinoids as potential targets for Alzheimer's disease.

 

Nutrition and Alzheimer's disease: pre-clinical concepts.

 

Novel analogs of choline as potential neuroprotective agents.

 

Multifunctional actions of approved and candidate stroke drugs.

 

Validation of in vivo MRS measures of metabolite concentrations in the human brain.

 

Intraperitoneal administration of CDP-choline and its cholinergic and pyrimidinergic metabolites induce hyperglycemia in rats: involvement of the sympathoadrenal system.

 

Discovery of Novel Acetylcholinesterase Inhibitors as Potential Candidates for the Treatment of Alzheimer's Disease.

 

Citicoline mechanisms and clinical efficacy in cerebral ischemia.

 

Citicoline--the first effective neuroprotectant to be combined with thrombolysis in acute ischemic stroke?

 

Neuroprotective agents in acute ischemic stroke.

 

Mediators of anaphylaxis and inflammation.

 

Neuroprotection by platelet-activating factor antagonism.

 

Vascular dementia: pharmacological treatment approaches and perspectives.

 

Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?

 

Citicoline in vascular cognitive impairment and vascular dementia after stroke.

 

Neuroenhancement and neuroprotection by oral solution citicoline in non-arteritic ischemic optic neuropathy as a model of neurodegeneration: A randomized pilot study.

 

Citicoline: update on a promising and widely available agent for neuroprotection and neurorepair.

 

Citicoline in pre-clinical animal models of stroke: a meta-analysis shows the optimal neuroprotective profile and the missing steps for jumping into a stroke clinical trial.

 

Neurorepair versus neuroprotection in stroke.

 

The best basic science paper in multiple sclerosis in 2014: citicoline, remyelination and neuroprotection: commentary.

 

Clinical use of cholinomimetic agents: a review.

 

Lipid signaling: sleep, synaptic plasticity, and neuroprotection.

 

Thrombolysis and neuroprotection in cerebral ischemia.

 

Glycerophospholipids and glycerophospholipid-derived lipid mediators: a complex meshwork in Alzheimer's disease pathology.

 

Pharmacodynamic, pharmacokinetic and pharmacogenetic aspects of drugs used in the treatment of Alzheimer's disease.

 

Functional characterization of α7 nicotinic acetylcholine and NMDA receptor signaling in SH-SY5Y neuroblastoma cells in an ERK phosphorylation assay.

 

The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF).

 

News about neuroprotectants for the treatment of stroke.

 

Molecular Signaling Mechanisms of Natural and Synthetic Retinoids for Inhibition of Pathogenesis in Alzheimer's Disease.

 

In vivo neurometabolic profiling in orthostatic tremor.

 

Facts, myths, and controversies in vascular dementia.

 

Progressive meningoencephalitis due to neurosarcoidosis.

 

Stimulating nicotinic receptors trigger multiple pathways attenuating cytotoxicity in models of Alzheimer's and Parkinson's diseases.

 

The pedunculopontine tegmental nucleus: from basic neuroscience to neurosurgical applications: arousal from slices to humans: implications for DBS.

 

The α7 nicotinic acetylcholine receptor: A mediator of pathogenesis and therapeutic target in autism spectrum disorders and Down syndrome.

 

Beyond the Hypothesis of Serum Anticholinergic Activity in Alzheimer's Disease: Acetylcholine Neuronal Activity Modulates Brain-Derived Neurotrophic Factor Production and Inflammation in the Brain.

 

Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia.

 

Tuftsin-phosphorylcholine (TPC) equally effective to methylprednisolone in ameliorating lupus nephritis in a mice model.

 

What have we learned from proton magnetic resonance spectroscopy about schizophrenia? A critical update.

 

Duration of Posttraumatic Amnesia Predicts Neuropsychological and Global Outcome in Complicated Mild Traumatic Brain Injury.

 

Bioactive lipids in excitatory neurotransmission and neuronal plasticity.

 

Combination of Neuroprotective and Regenerative Agents for AGE-Induced Retinal Degeneration: In Vitro Study.

 

Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy.

 

The effect of drugs for Alzheimer disease assessed by means of neuroradiological techniques.

 

Insular cortex metabolite changes in obstructive sleep apnea.

 

(1)H-magnetic resonance spectroscopy in social anxiety disorder.

 

Combined Cerebellar Proton MR Spectroscopy and DWI Study of Patients with Friedreich's Ataxia.

 

Lipoic acid as a novel treatment for Alzheimer's disease and related dementias.

 

Evidence of the neuroprotective role of citicoline in glaucoma patients.

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